Sitostanol formulation with emulsifier to reduce cholesterol absorption

Formulation de sitostanol a emulsifiant permettant de reduire l'absorption de cholesterol

Abstract

Compositions useful to reduce cholesterol absorption. The compositions may be dosed in capsule or tablet form, or by adding either in liquid or dry powder form to foods and beverages. The compositions are an aqueous based homogeneous micellar mix which is dried to provide a mixture of finely-divided plant sterol, preferably sitostanol and lecithin. The mole ratio of the plant sterol, preferably sitostanol to lecithin, should be within the range of 1:0.1 to 1:10, preferably at least 1:2.
L'invention concerne des compositions qui permettent de réduire l'absorption de cholestérol. Ces compositions peuvent être dosées en capsules ou en comprimés, ou bien sous forme de liquide ou de poudre sèche à ajouter à des aliments ou à des boissons. Lesdites compositions constituent un mélange micellaire homogène aqueux que l'on sèche pour établir un mélange à base de stérol végétal finement divisé (de préférence sitostanol) et de lécithine. Le rapport moléculaire entre ce stérol (de préférence sitostanol) et la lécithine, doit être compris entre 1:0,1 et 1:10, et il sera de préférence égal au moins à 1:2.

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NO-Patent Citations (1)

    Title
    DATABASE WPI Section Ch Week 9119, Derwent Publications Ltd., London, GB; Class B04, AN 91-137940, XP002110288

Cited By (6)

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    EP-1082026-A1March 14, 2001Forbes Medi-Tech Inc.Compositions comprising phytosterol and/or phytostanol having enhenced solubility and dispersa
    RU-2485808-C2June 27, 2013Эдио Хэлткеар АбComposition with phytosterols of high bioavailability
    US-9078464-B2July 14, 2015Edio Healthcare AbCompositions of phytosterols with enhanced bioavailability
    WO-0047213-A1August 17, 2000Washington UniversitySitostanol formulation with emulsifier to reduce cholesterol absorption and method for preparing and use of same
    WO-0100046-A1January 04, 2001Cognis Deutschland GmbhUse of nanoscale sterols and sterol esters
    WO-2009099392-A1August 13, 2009Edio Healthcare AbCompositions of phytosterols with enhanced bioavailability